Question:
"I have tried to install the software Prism desktop
software several times. Each time I receive an error 1603: Error
installing Microsoft(R) .Net Framework."
Seems to be a Microsoft issue, here is a possible solution :
http://forums.microsoft.com/WindowsHomeServer/ShowPost.aspx?PostID=3332279&SiteID=50
I also find the following link which worked as well. You might like to have a look at it.
http://turbotax.intuit.com/support/kb/installing/errors/5193.html